(DOWNLOAD) "Cardiac Regeneration and Repair" by Ren-Ke Li & Richard D. Weisel # eBook PDF Kindle ePub Free
eBook details
- Title: Cardiac Regeneration and Repair
- Author : Ren-Ke Li & Richard D. Weisel
- Release Date : January 17, 2014
- Genre: Engineering,Books,Professional & Technical,
- Pages : * pages
- Size : 15301 KB
Description
Heart disease is the leading cause of death in the Western World and heart failure following a myocardial infarction continues to increase despite urgent revascularization. Cell therapy offered the promise to reverse cardiac injury and prevent heart failure, but the initial clinical trials were not as effective as anticipated. New approaches to restore ventricular function are urgently needed. Cardiac regeneration and repair Volume 2 reviews the use of biomaterials, alone or combined with cell therapy, to provide tissue engineered constructs to repair the injured heart and prevent or reverse heart failure.
Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy to restore ventricular function and to generate stem cell modified intravascular stents. Part two focuses on tissue engineering for cardiac repair including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodelling including chapters highlighting aortic extra cellular matrix remodelling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels.
Cardiac regeneration and repair Volumes 1 and 2 provide a comprehensive resource for clinicians, scientists or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering or biomaterials.
Explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy to restore ventricular function and to generate stem cell modified intravascular stentsFocuses on tissue engineering for cardiac repair including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineeringExplores vascular remodelling including chapters highlighting aortic extra cellular matrix remodelling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels